Medical News

Patients who received direct oral anticoagulants (DOACs) following transcatheter mitral valve replacement (TMVR) seem to have a lower risk of bleeding complications and shorter length of hospital stay, with no significant increase in the risk of thrombotic events, than those treated with vitamin K antagonists (VKAs), a study has shown.

Multiple factors contribute to the low uptake of evidence-based medical therapy (EBMT) in the management of peripheral artery disease (PAD), reports a Singapore study.

Maintaining good cardiovascular health (CVH) can help avert incident adult-onset asthma (AOA) regardless of a person’s asthma genetic risks, according to a study.

In critically ill patients who have been on invasive mechanical ventilation (IMV) for at least 3 days, a subsequent 3-day course of preventive inhaled amikacin reduced the burden of ventilator-associated pneumonia (VAP) during 28 days of follow-up, findings from the AMIKINHAL trial have shown.

Treatment with the combination of xanomeline plus trospium leads to favourable reduction in positive and negative symptoms in patients with schizophrenia, while being well tolerated, according to data from the phase III EMERGENT-2 trial.

Dietary nitrate supplementation for patients with chronic obstructive pulmonary disease (COPD) appears to lead to better exercise capacity, according to a study.

The tricyclic antidepressant amitriptyline, when used at low dose in the second-line treatment setting and titrated according to symptom response and side-effects, is safe and provides relief from symptoms of irritable bowel syndrome (IBS), as shown in the phase III ATLANTIS* trial.

People who consume a lot of ultra-processed food (UPF) have a greater risk of developing nonalcoholic fatty liver disease (NAFLD), liver fibrosis, and cirrhosis, as well as severe liver disease and adverse levels of several clinical biomarkers, reveals a study.

Use of allopurinol 300 mg helps prevent the incidence of overall complications associated with liver cirrhosis, reports a study.

Taking cocoa extract (CE) supplements daily appears to be no better than placebo in improving the cognitive function of older adults who underwent repeat in-person, detailed neuropsychological assessments over 2 years, a study has shown.