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CROUP

Croup is a viral infection that causes erythema and edema of the tracheal walls and narrowing of the subglottic region. It is often characterized by an acute, rapidly progressing respiratory disease.
It is a medical emergency in children and requiring immediate treatment.
Most common causes are parainfluenza virus 1&2 and respiratory syncytial virus.
Occurrence of symptoms is usually at night and with abrupt onset and improve during daytime.

Croup Signs and Symptoms

Signs and Symptoms

Introduction

Croup is often characterized by an acute, rapidly progressing respiratory disease

Also referred to as laryngotracheitis, laryngotracheobronchitis, & laryngotracheobronchopneumonitis
Common cause of upper respiratory tract obstruction in children
Rarely occurs in adults
Often self-limiting but may possibly cause severe respiratory obstruction
Develops concurrent w/ coryzal disease

Etiology

Most common causes of croup:
- Parainfluenza virus 1-3 (type 1 being most common)
- Respiratory syncytial virus

Signs and Symptoms

Occurrence of symptoms is usually at night & w/ abrupt onset, & improve during daytime
- Barking cough
- Dyspnea, w/ possible rapid progression to airway obstruction
- Hoarse voice
- Inspiratory stridor may be severe & may herald complete airway obstruction
- Fever may or may not occur

Combined Ag/Ab rapid testing boosts case-finding in COVID-19

Elvira Manzano, 29 Jul 2021

A rapid and affordable test for diagnosing COVID-19 outside the walls of the healthcare units could improve case-finding, contact tracing, and infection control, says an expert during a pre-ECCMID 2021 session.

Product Highlight - Oncaspar

14 Sep 2023

Pegaspargase powder for solution for injection/infusion 3,750 units

Immunotherapy sparks hope for paediatric ALL

Audrey Abella, 14 Oct 2020

Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.