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Nurtec

Nurtec

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Rimegepant sulfate
Indications/Uses
Acute treatment of migraine w/ or w/o aura in adults. Preventive treatment of episodic migraine in adults w/ at least 4 migraine attacks mthly.
Dosage/Direction for Use
Acute treatment of migraine 75 mg once daily. Prophylaxis of migraine 75 mg every other day. Max: 75 mg daily.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Discontinue use if hypersensitivity reactions eg, dyspnoea, rash occur. Avoid next dose w/in 48 hr when concomitantly administered w/ moderate CYP3A4 inhibitors. Not recommended for concomitant use w/ strong CYP3A4 inhibitors & strong or moderate CYP3A4 inducers. Medication overuse headache. Not recommended in patients w/ severe hepatic impairment; ESRD (CrCl <15 mL/min). Severe renal impairment; dialysis patients. Avoid use during pregnancy. Lactation. Paed <18 yr.
Drug Interactions
Increased plasma conc w/ CYP3A4 inhibitors eg, clarithromycin, itraconazole, ritonavir; P-gp & BCRP efflux transporters eg, cyclosporine, verapamil, quinidine. Increased exposure w/ moderate CYP3A4 inhibitors eg, diltiazem, erythromycin, fluconazole. Decreased plasma conc w/ strong (eg, phenobarb, rifampicin, St. John's wort) or moderate (eg, bosentan, efavirenz, modafinil) CYP3A4 inducers.
MIMS Class
Antimigraine Preparations
ATC Classification
N02CD06 - rimegepant ; Belongs to the class of calcitonin gene-related peptide (CGRP) antagonists preparations. Used to relieve migraine.
Presentation/Packing
Form
Nurtec oral lyophilisate 75 mg
Packing/Price
1 × 2's;1 × 8's
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